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  TALEN Gene Target Service  

   Monoclonal Antibody

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Custom TALEN Gene Target Services

Transcription Activator-Like Effector Nucleases (TALENs) are a novel class of engineered DNA-binding protein that facilitate targeted editing of the genome by creating double-strand breaks in DNA at user-specific locations.  Double-strand breaks are important for site-specific mutagenesis in that they stimulate the cell’s natural DNA-repair process, namely homologous recombination and non-homologous end joining, resulting in precisely targeted genomic edits in cell line with targeted gene deletions, integrations, or modifications.  

     Target sequence confirmed by both customer and Vicgene

     Constructing Custom TALEN gene target cleavage plasmids (2 plasmids of a Transcription Activator-Like Effector fused to a nuclease catalytic domain).

     TALEN gene target cleavage plasmid sequence verified

     Custom TALEN gene target cleavage plasmids delivered in a pair of expression plasmids

 

Delivery Timeframe

Within 2-4 weeks after sequence submission

Limitation of Use

Research Use Only