Custom TALEN Gene Target Services
Activator-Like Effector Nucleases (TALENs) are a novel class of engineered
DNA-binding protein that facilitate targeted editing of the genome by creating
double-strand breaks in DNA at user-specific locations.
Double-strand breaks are important for site-specific mutagenesis in that
they stimulate the cell’s natural DNA-repair process, namely homologous
recombination and non-homologous end joining, resulting in precisely targeted
genomic edits in cell line with targeted gene deletions, integrations, or
Target sequence confirmed by both customer and Vicgene
Constructing Custom TALEN gene target cleavage plasmids (2 plasmids of a
Transcription Activator-Like Effector fused to a nuclease catalytic domain).
TALEN gene target cleavage plasmid sequence verified
Custom TALEN gene target cleavage plasmids delivered in a pair of
2-4 weeks after sequence submission